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Cocaine is an ester local anesthetic used in or through the nasal cavities for diagnostic and surgical procedures. ChemsPowder has cocaine for sale at reasonable prices for everyone. If you want to buy something, our online store is the place to go. We will assist you in obtaining this product in a timely manner. Cocaine Powder for Sale

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An alkaloid ester is derived from plant leaves, such as coca leaves. It is a local anesthetic and vasoconstrictor that is commonly used in the eye, ear, nose, and throat. It is also abused and has powerful central nervous system effects similar to amphetamines. Cocaine, like amphetamines, affects brain catecholaminergic neurons through a variety of mechanisms. Buy Cocaine Powder Online

What is the Cocaine Indication?

To apply a local (topical) anesthetic to the accessible mucosal membranes of the oral, laryngeal, and nasal cavities.

Action Mechanism

Cocaine produces anesthesia by decreasing nerve-ending stimulation or restricting nerve conduction in peripheral nerves. This is accomplished by binding to and inactivating sodium channels reversibly. Sodium inflow through these channels is required for depolarization of nerve cell membranes and subsequent impulse propagation along the course of the nerve. Cocaine is the only local anesthetic with vasoconstriction effects. This is caused by a blockage of norepinephrine reuptake in the autonomic nervous system. Cocaine binds to dopamine, serotonin, and norepinephrine transport proteins in different ways, preventing them from being reabsorbed into presynaptic neurons. The addictive properties of cocaine are primarily. Buy Cocaine Powder Online

Absorption
Cocaine is absorbed through the gastrointestinal tract’s mucous membranes and mucosa. 60% to 80% of cocaine is absorbed orally or intravenously.

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